Project 4

Are Mutations In Alport Syndrome Genes Associated With Encapsulating Peritoneal Sclerosis (EPS)?

Encapsulating peritoneal sclerosis” is life-threatening complication in people undergoing peritoneal dialysis. The inside of their abdomen becomes scarred and the dialysis stops working. Patients often become very sick and require complicated surgical treatment. We don’t know why some people get this disease or how to treat it. Some people may be at risk of developing this condition because of their genes, and we will look at the genetic risk factors. The findings from this study could ultimately translate to a genetic screen for patients considering PD, to indicate the likely risk of developing a severely fibrosed peritoneal membrane.