Appointed as Consultant at the MRI in 1999. After appointment, led the revival and development of the pancreas transplant programme in Manchester (2001) following a short sabbatical to the University of Minnesota. Manchester is currently the second largest pancreas transplant programme in the UK. The MRI has performed the first non-heart beating pancreas transplant, the first pancreas re-transplant and transplants in the youngest and oldest recipients to date in the UK. In 2002 introduced laparoscopic hand assisted donor nephrectomy. Currently mentoring consultant colleagues in the procedure. In 2005, introduced laparoscopic adrenalectomy. In 2007 started developing a national surgical service for encapsulating peritoneal sclerosis. Member of the United Kingdom Pancreas Task Force, British Transplantation Society Training Committee member and member of the UK EPS Research Group. Several publications with research interests in Pancreas Transplantation and surgery for Encapsulating Peritoneal Sclerosis.
Titus is also a Trustee of Kidneys for Life.