Rachel is a Professor of Nephrology at the University of Manchester and a Consultant Paediatric Nephrologist. The research in Rachel’s group is focused on understanding the causes of glomerular disease, which is the leading cause of chronic kidney disease in adults and children. The glomerular capillary wall is a highly sophisticated filtration barrier that comprises specialised cells and supporting structures known as basement membranes. Rachel’s team have developed techniques to study basement membrane regulation including proteomic methods and high resolution imaging. Using a combination of in vitro systems (glomerular cell coculture, kidney organoids) and animal models (mouse, zebrafish) the Lennon Lab now seek to understand mechanisms of glomerular barrier injury and repair.
Rachel is also a Trustee of Kidneys for Life.